156-54-7丁酸钠,98%

CAS号： 156-54-7

分子式： C4H7NaO2 分子量： 110.09

• 丁酸钠

  英文名：sodium butyrate

  CAS：	156-54-7	精确质量：	110.03400
  分子式：	C4H7NaO2	LogP：	-0.46360
  分子量：	110.08700	PSA：	40.13000

156-54-7丁酸钠,98%化合物描述

Sodium butyrate is a compound with formula Na(C3H7COO). It is the sodium salt of butyric acid. It has various effects on cultured mammalian cells including inhibition of proliferation, induction of differentiation and induction or repression of gene expression. As such, it can be used in lab to bring about any of these effects. Specifically, butyrate treatment of cells results in histone hyperacetylation, and butyrate itself inhibits class I histone deacetylase (HDAC) activity, specifically HDAC1, HDAC2, HDAC3, and HDAC8. Butyrate has been an essential vehicle for determining the role of histone acetylation in chromatin structure and function. Inhibition of HDAC activity is estimated to affect the expression of only 2% of mammalian genes.
In the lab, sodium butyrate is usually found as a white, water-soluble, crystalline solid. The chemical is notable for having a very strong, unpleasant smell that lingers. When working with sodium butyrate, gloves, eye protection and respiratory masks are advised for safety purposes.
The compound is found in human diet, notably produced in large amounts from dietary fiber in the gut and present in Parmesan cheese and butter.

156-54-7丁酸钠,98%基本信息

• 中文名称：

  丁酸钠

• 中文别名：

  丁酸钠盐;
  

• 英文名称：

  sodium butyrate

• 英文别名：

  Natriumbutyrat;
  Butyrate sodium salt;
  NAB;
  BUTYRIC ACID NA;
  SODIUMBUTYRATE,USP;
  sodium n-butyrate;
  Sodium butanoate;
  Sodium Butyrate;
  SODIUM N-BUTYLATE;
  SODIUM BUTYRATE;
  Na butyrate;
  Sodium butyrate;
  butyratesodium;
  SODIUM BUTYRATE pure;
  butyric acid sodium salt;
  Butyric Acid Sodium Salt;
  

• CAS号：

  156-54-7

• 分子式：

  C4H7NaO2

• 分子量：

  110.08700

• 精确质量：

  110.03400

• PSA：

  40.13000

• LogP：

  -0.46360

物化性质

• 外观与性状：

  白色粉末

• 密度：

  0.987g/cm3

• 熔点：

  250-253 °C(lit.)

• 沸点：

  164.3oC at 760 mmHg

• 闪点：

  69.7oC

• 水溶解性：

  soluble

• 稳定性：

  Stable. Incompatible with strong acids.

• 储存条件：

  库房低温,通风,干燥

• 蒸汽压：

  1.35mmHg at 25°C

安全信息

• RTECS号：

  ET6400000

• WGK Germany：

  1

• 安全说明：

  S37/39-S26-S24/25

• 危险品运输编码：

  2820

• 危险品标志：

  Xi

• 危险类别码：

  R36/37/38

• 海关编码：

  2915600000

生产方法及用途

• 用途

  广泛用于畜禽饲料添加中，可以提高采食量、饲料报酬和日增重。增强动物健康水平。减少腹泻和死亡率。