867-44-7S-甲基异硫脲硫酸盐,98%

CAS号： 867-44-7

分子式： C2H8N2O4S2 分子量： 139.18

• S-甲基异硫脲半硫酸盐

  英文名：2-Methyl-2-thiopseudourea sulfate

  CAS：	867-44-7	精确质量：	187.99300
  分子式：	C2H8N2O4S2	LogP：	1.47090
  分子量：	188.22600	PSA：	158.15000

867-44-7S-甲基异硫脲硫酸盐,98%化合物描述

Intermediate of 4-Hydroxydebrisoquine. S-Methyl-isothiouronium Hemisulfate is also a reagent used in the synthesis of strobilurin-pyrimidine derivatives for their anti-proliferative activity.

867-44-7S-甲基异硫脲硫酸盐,98%基本信息

• 中文名称：

  S-甲基异硫脲半硫酸盐

• 中文别名：

  JS-甲基异硫脲硫酸盐;
  S-甲基-ITU;
  2-甲基异硫脲硫酸盐;
  甲基异硫脲硫酸盐;
  S-甲基异硫脲;
  2-甲基-2-疏基硫酸脲;
  2-甲基-2-硫代假脲半硫酸盐;
  2-甲基-2-硫代异尿素硫酸盐;
  

• 英文名称：

  2-Methyl-2-thiopseudourea sulfate

• 英文别名：

  S-METHYLTHIOURONIUM SULFATE FOR SYNTHESIS;
  S-Methylisothiourea hemisulfate;
  S-METHYL ISOTHIOUREA SULFATE;
  methyl imidothiocarbamate;
  S-methylisothiourea hydrogensulfate;
  S-METHYL-ISO-THIOUREA SULFATE;
  S-EIT hemihydrate;
  S-METHYLISOTHIOURONIUM SULFATE;
  S-Methylisothiourea Hemisulfate Salt;
  S-methyl-2-thiopseudourea hydrogen sulfate;
  S-METHYL-ISO-THIOUREA;
  S-Methyl-isothiouronium Hemisulfate;
  S-METHYLISOTHIOUREA HEMISULFATE SALT _X000D_;
  2-Methyl-2-thiopseudourea hemisulfate;
  S-METHYLISOTHIOURONIUM SULPHATE/S-METHYLISOTHIOUREA SULPHATE/2-METHYL-2-THIOPSEUDOUREA SULPHATE;
  methyl imidothiocarbamate sulfate;
  S-METHYLISOTHIOUREASULFATE;
  S-Methyl-ITU;
  S-methylisothiouronium hydrogensulfate;
  (S)-METHYLISOTHIOUREA SULFATE;
  S-Methyl-ITU . sulfate;
  2-METHYL-2-THIOPSEUDO UREA 14C SULFATE;
  S-METHYLTHIOPSEUDOUREA SULPHATE;
  S-Methylisothiourea sulfate;
  Carbamimidothioic acid, methyl ester, sulfate (2:1);
  S-METHYLTHIOURONIUMSULFATE(2:1);
  2-Methyl-2-thiopseud;
  S-Methylisothiourea hemisulfate salt;
  S-methyl Isothiourea (hemisulfate);
  S-METHYL-2-ISOTHIOUREA HEMISULPHATE;
  METHYLTHIURONIUMSULPHATE;
  METHYLTHIOURONIUMSULPHATE;
  S-Methyl isothiourea sulfate;
  2-Methyl-2-thiopseudoureasulfate;
  S-METHYLISOTHIOURONIUM SULPHATE;
  5-METHYLISOTHIOUREA HEMISULFATE;
  2-methyl-2-thiopseudouronium sulfate;
  methyl carbamimidothioate;
  IMINO(METHYLSULFANYL)METHYLAMINE;
  S-MethyliSothourea Sulfate;
  2-METHYL-2-THIOPSEUDOUREA SULFATE (S-METHYLISOTHIOUREA SULFATE);
  S-methyl isothiourea sultate;
  S-METHYLTHIOURONIUM SULFATE;
  S-methylisothiourea sulfuric acid salt 1:1;
  S-METHYLTHIOUREA;
  S-METHYLISOTHIOHARNSTOFF HEMISULFAT;
  

• CAS号：

  867-44-7

• 分子式：

  C2H8N2O4S2

• 分子量：

  188.22600

• 精确质量：

  187.99300

• PSA：

  158.15000

• LogP：

  1.47090

物化性质

• 外观与性状：

  白色结晶粉末

• 密度：

  1.28

• 熔点：

  240-241 °C (dec.)(lit.)

• 沸点：

  138.8oC at 760 mmHg

• 闪点：

  37.7oC

• 水溶解性：

  260 g/L (20 oC)

• 稳定性：

  Stable. Incompatible with strong oxidizing agents.

• 储存条件：

  Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.

安全信息

• RTECS号：

  UM9200000

• WGK Germany：

  3

• 安全说明：

  S22-S24/25

• 海关编码：

  2930909090

• 危险品标志：

  Xn

• 危险类别码：

  R22

生产方法及用途

• 生产方法

  其制备方法是将硫脲加入反应器中加入少许水,在搅拌情况下使硫脲部分溶解,冷水浴冷却下搅拌10min,再加入重蒸的硫酸二甲酯,迅速安装上两根球形冷凝管,以防暴沸,撤去冷水浴,反应自发进行放热,5min后突然暴沸,此时固体已大部分溶解,待回流减弱并平衡后,加热再回流1h,静置过夜,反应物固化,加入95%乙醇搅拌片刻,冰水冷却0.5h,过滤,用25%乙醇洗涤得成品。

• 用途

  医药中间体。