532-43-4硝酸硫胺,98%

CAS号： 532-43-4

分子式： C12H17N5O4S 分子量： 327.4

• 硝酸硫胺

  英文名：Thiamine nitrate

  CAS：	532-43-4	精确质量：	327.10000
  分子式：	C12H17N5O4S	LogP：	1.47300
  分子量：	327.35900	PSA：	173.03000

532-43-4硝酸硫胺,98%化合物描述

Thiamine mononitrate is a stable nitrate salt form of thiamine (vitamin B1). It occurs as a white crystalline powder and is prepared from thiamine hydrochloride. It is used as a food or nutritional supplement and is the preferred form of the vitamin for food fortification. Thiamin mononitrate is used in the pharmaceutical industry to treat beriberi and general malnutrition or malabsorption. Thiamine can be found naturally in foods like grains, yeast, molasses, pork and animal organ meats. Dairy, eggs and legumes have smaller amounts.
Though thiamine is found naturally in foods, thiamine mononitrate is not. Thiamine mononitrate is synthesized by removing a chloride ion from thiamin hydrochloride and mixing the final product with nitric acid. Thiamine hydrochloride is hygroscopic (water-absorbing) whereas the mononitrate has almost no hygroscopic properties. For this reason, the mononitrate is the more stable form of the vitamin in fortified flours and cereals.
Thiamine mononitrate is also specifically known as mononitrate de thiamine, nitrate de thiamine, and thiamine nitrate. In addition, as a vitamer of thiamine, it is also known by all the generic names of thiamine, such as thiamine, antiberiberi factor, antiberiberi vitamin, antineuritic factor, antineuritic vitamin, facteur anti-béribéri, facteur antineuritique, tiamina, vitamin B1, vitamin B-1, vitamina B1, vitamine anti-béribéri, vitamine antineuritique, vitamine B1.

532-43-4硝酸硫胺,98%基本信息

• 中文名称：

  硝酸硫胺

• 中文别名：

  维生素B1硝酸盐;
  

• 英文名称：

  Thiamine nitrate

• 英文别名：

  Vitanon;
  Thiamin mononitrate;
  Vitamin B1 nitrate;
  Thiamine Nitrate;
  Thiaminnitrat;
  VitaMin B1 HNO3;
  Vitamin B1 Mono;
  Thaimenitrate;
  Thiaminenitrate;
  thiamine,nitrate;
  Thiamine nitrate,Vitamin B1 nitrate;
  mnitrate;
  thiamin nitrate;
  thiaminium nitrate;
  

• CAS号：

  532-43-4

• 分子式：

  C12H17N5O4S

• 分子量：

  327.35900

• 精确质量：

  327.10000

• PSA：

  173.03000

• LogP：

  1.47300

物化性质

• 外观与性状：

  白色晶体粉末

• 熔点：

  196-200°C

• 稳定性：

  Stable. Incompatible with strong oxidizing agents.

安全信息

• RTECS号：

  XI7400000

• 安全说明：

  S22-S24/25

• 海关编码：

  2934100090

生产方法及用途

• 生产方法

  维生素B1自然存在于米糠、麸皮、瘦肉、花生米等食物中,纯品通常由化学合成制备。过量的盐酸乙脒在碱性(甲醇和甲醇钠)介质中与α-二甲氧基-β-甲氧基丙腈缩合为3,6-二甲基-1,2-二氢-2,4,5,7-四氮萘,然后在98-100℃下水解,再在碱性条件下开环生成2-甲基-4-氨基-5-氨甲基嘧啶;接着与二硫化碳和氨水作用,然后与乙酸-γ-氯代-γ-乙酰丙酯缩合,再在盐酸中、75-78℃下水解和环合成硫代硫胺盐酸盐,*用氨水中和、过氧化氢氧化、盐酸酸化得硫胺盐酸盐。

• 用途

  维生素B1，是维持神经及消化系统正常功能的一种重要水溶性维生素，参与体内辅酶的形成，维持糖代谢。